Synthesis and structure–activity relationship of botryllamides that block the ABCG2 multidrug transporter

K Takada, N Imamura, KR Gustafson…

文献索引：Takada, Kentaro; Imamura, Nobutaka; Gustafson, Kirk R.; Henrich, Curtis J. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 4 p. 1330 - 1333

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被引用次数: 20

摘要

In previous work, botryllamides discovered from the marine ascidian Botryllus tyreus were characterized as selective inhibitors of the ABCG2 multidrug transporter. However, the structural basis for this activity could not be established. In this study, botryllamide F, the ...