Palladium-nanoparticle-catalyzed 1, 7-palladium migration involving C–H activation, followed by intramolecular amination: regioselective synthesis of N 1- …

…, Y Shiro, H Fukuda, S Shuto, M Arisawa

文献索引：Hoshiya, Naoyuki; Shimoda, Masahiko; Yoshikawa, Hideki; Yamashita, Yoshiyuki; Shuto, Satoshi; Arisawa, Mitsuhiro Journal of the American Chemical Society, 2010 , vol. 132, # 21 p. 7270 - 7272

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被引用次数: 17

摘要

A sulfur-modified gold-supported palladium material (SAPd) has been developed bearing palladium nanoparticles on its surface. Herein, we report for the first time the use of SAPd to affect a Pd-nanoparticle-catalyzed 1, 7-Pd migration reaction for the synthesis of benzotriazoles via C–H bond activation. The resulting benzotriazoles were evaluated in terms of their inhibitory activity toward indoleamine 2, 3-dioxygenase.