Versatile catalysts for the Suzuki cross-coupling of arylboronic acids with aryl and vinyl halides and triflates under mild conditions

AF Littke, C Dai, GC Fu

文献索引：Littke, Adam F.; Dai, Chaoyang; Fu, Gregory C. Journal of the American Chemical Society, 2000 , vol. 122, # 17 p. 4020 - 4028

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被引用次数: 1438

摘要

Through the use of Pd2 (dba) 3/P (t-Bu) 3 as a catalyst, a wide range of aryl and vinyl halides, including chlorides, undergo Suzuki cross-coupling with arylboronic acids in very good yield, typically at room temperature; through use of Pd (OAc) 2/PCy3, a diverse array of aryl and vinyl triflates react cleanly at room temperature. Together, these two catalyst systems cover a broad spectrum of commonly encountered substrates for Suzuki ...