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Characterization of d??boroAla as a Novel Broad??Spectrum Antibacterial Agent Targeting d??Ala??d??Ala Ligase

S Putty, A Rai, D Jamindar, P Pagano…

文献索引:Putty, Sandeep; Rai, Aman; Jamindar, Darshan; Pagano, Paul; Quinn, Cheryl L.; Mima, Takehiko; Schweizer, Herbert P.; Gutheil, William G. Chemical Biology and Drug Design, 2011 , vol. 78, # 5 p. 757 - 763

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被引用次数: 6

摘要

Materials and Methods Synthesis of boro-amino acid analogs The synthesis strategy for alkyl side chain D-boro-amino acid analogs was adapted from general procedures for L- boro analogs developed by Matteson, Kettner et al.(14–16) and described previously (11)(Scheme 1). The synthesis strategy used for boroGly pinacol is outlined in Scheme 2.