Synthetic communications

Synthesis of 1, 1??Dimethyl??4??indanol Derivatives

Y Wang, J Wu, P Xia

文献索引：Wang, Yang; Wu, Jiang; Xia, Peng Synthetic Communications, 2006 , vol. 36, # 18 p. 2685 - 2698

全文：HTML全文

被引用次数: 10

摘要

Abstract The synthesis of 1, 1??dimethyl??4??indanols (3a, b) has been achieved by intramolecular Friedel–Crafts cyclization of 2??(3??methyl??2??butenyl) phenols (5a, b) or 1?? methoxy??2??(3??methyl??2??butenyl) benzenes (6a, b) followed by demethylation, respectively. It was found that the solvent was critical for the formation of different products in the intramolecular Friedel–Crafts reactions of 6. The unexpected product 4??methoxy??1, 1, 6, 6 ...