Synthesis of coumestan derivatives via FeCl3-mediated oxidative ring closure of 4-hydroxy coumarins

L Tang, Y Pang, Q Yan, L Shi, J Huang…

文献索引：Tang, Lina; Pang, Yongle; Yan, Qiao; Shi, Liuqing; Huang, Jianhui; Du, Yunfei; Zhao, Kang Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2744 - 2752

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被引用次数: 41

摘要

A concise and efficient approach to the syntheses of coumestan analogues has been developed. The underpinning strategy involves a FeCl3-mediated direct intramolecular oxidative annellation of 4-hydroxy-3-phenyl-2 H-chromen-2-one derivatives. Utilizing this synthetic protocol, a variety of coumestan derivatives were conveniently obtained from readily available reagents.