Synlett

Reductive amination promoted by tributyltin hydride

T Suwa, E Sugiyama, I Shibata, A Baba

文献索引：Suwa, Toshihiro; Sugiyama, Erika; Shibata, Ikuya; Baba, Akio Synlett, 2000 , # 4 p. 556 - 558

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被引用次数: 32

摘要

Abstract: Reductive amination of carbonyl compounds with primary and secondary ammonium salts was performed by tributyltin hydride in DMF solvent at room temperature. A variety of secondary and tertiary amines including sterically hindered ones could be synthesized in one-pot procedure. No side reaction such as the reduction of starting carbonyl or overalkylation was detected. Key words: reductive amination, tin hydride, ...