前往化源商城

Tetrahedron

Practical one-pot conversion of aryl bromides and β-bromostyrenes into aromatic nitriles and cinnamonitriles

G Ishii, R Harigae, K Moriyama, H Togo

文献索引:Ishii, Genki; Harigae, Ryo; Moriyama, Katsuhiko; Togo, Hideo Tetrahedron, 2013 , vol. 69, # 5 p. 1462 - 1469

全文:HTML全文

被引用次数: 13

摘要

Various aryl bromides were efficiently converted into the corresponding aromatic nitriles in good yields by the treatment with Mg turnings and subsequently DMF, followed by treatment with molecular iodine and aq NH3. The same treatment of aryl bromides, which are weakly reactive to Mg turnings, with iPrMgCl· LiCl and subsequently DMF, followed by the treatment with molecular iodine and aq NH3 also afforded the corresponding aromatic nitriles in ...

 相关合成线路

~62%

~85%

~60%

~69%

~59%

~78%

~62%

~72%

~74%

~73%

~69%

~65%

~50%

~76%

~81%

~62%

~52%

~62%

~68%

~82%

~65%

~83%

~63%

~63%

~70%