Tetrahedron Letters

A rapid access to coumarin derivatives (using Vilsmeier–Haack and Suzuki cross-coupling reactions)

S Hesse, G Kirsch

文献索引：Hesse, Stephanie; Kirsch, Gilbert Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1213 - 1215

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被引用次数: 66

摘要

Several polycyclic natural products with a coumarinic moiety display a large number of biological properties (anti-bacterial, 1., and anti-tumoral, 2 anti-HIV 3., , , and …). Due to those varied biological activities, a considerable amount of synthetic work in the field of coumarins with [3,4]-carbocyclic or [3,4]-heterocyclic fused ring systems has been done 4 . Classical reactions (such as Pechmann condensation, Michaël addition…) are still used but the development of ...