Chemistry–A European Journal

Synthesis of trans??Disubstituted Alkenes by Cobalt??Catalyzed Reductive Coupling of Terminal Alkynes with Activated Alkenes

S Mannathan, CH Cheng

文献索引：Mannathan, Subramaniyan; Cheng, Chien-Hong Chemistry - A European Journal, 2012 , vol. 18, # 37 p. 11771 - 11777

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被引用次数: 13

摘要

Abstract A cobalt-catalyzed reductive coupling of terminal alkynes, RC [TRIPLE BOND] CH, with activated alkenes, R′ CH [DOUBLE BOND] CH 2, in the presence of zinc and water to give functionalized trans-disubstituted alkenes, RCH [DOUBLE BOND] CHCH 2 CH 2 R′, is described. A variety of aromatic terminal alkynes underwent reductive coupling with activated alkenes including enones, acrylates, acrylonitrile, and vinyl sulfones in the ...