Design, Synthesis, and Biological Evaluation of Novel Transrepression-Selective Liver X Receptor (LXR) Ligands with 5, 11-Dihydro-5-methyl-11-methylene-6 H- …

A Aoyama, K Endo-Umeda, K Kishida…

文献索引：Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7360 - 7377

被引用次数: 17

摘要

... Journal of Medicinal Chemistry. ... serious hypertriglyceridemia because genes involved in lipid synthesis, such as srebp-1c and fas, have LXRE in their promoter region and are activated by LXR transactivational agonists.(8) This is a major barrier to medical application of LXR ...

394-31-0

5-羟基邻氨基苯甲酸

54413-93-3

2-碘-5-甲氧基苯甲酸

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