Design, Synthesis, and Biological Evaluation of Novel Transrepression-Selective Liver X Receptor (LXR) Ligands with 5, 11-Dihydro-5-methyl-11-methylene-6 H- …

A Aoyama, K Endo-Umeda, K Kishida…

Index: Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7360 - 7377

Full Text: HTML

Citation Number: 17

Abstract

... Journal of Medicinal Chemistry. ... serious hypertriglyceridemia because genes involved in lipid synthesis, such as srebp-1c and fas, have LXRE in their promoter region and are activated by LXR transactivational agonists.(8) This is a major barrier to medical application of LXR ...

Hypervalent iodine (III)-LiX combination in fluoroalcohol so...

[Hamamoto, Hiromi; Hattori, Sho; Takemaru, Kaori; Miki, Yasuyoshi Synlett, 2011 , # 11 p. 1563 - 1566]

Organoiodinane oxyanions as reagents for the cleavage of a r...

[Moss, Robert A.; Chatterjee, Swati; Wilk, Boguslawa Journal of Organic Chemistry, 1986 , vol. 51, # 22 p. 4303 - 4307]

2-Iodoxybenzenesulfonic acid as an extremely active catalyst...

[Uyanik, Muhammet; Akakura, Matsujiro; Ishihara, Kazuaki Journal of the American Chemical Society, 2009 , vol. 131, p. 251 - 262]

Chemoselective Deprotonative Lithiation of Azobenzenes: Reac...

[Nguyen, Thi-Huu; Chau, Nguyet Trang Thanh; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques Organic Letters, 2005 , vol. 7, # 12 p. 2445 - 2448]

Organoiodinane oxyanions as reagents for the cleavage of a r...

[Journal of Organic Chemistry, , vol. 51, # 22 p. 4303 - 4307]