Tetrahedron letters

A novel linker strategy for solid-phase synthesis

JR Morphy, Z Rankovic, DC Rees

文献索引：Morphy, J. Richard; Rankovic, Zoran; Rees, David C. Tetrahedron Letters, 1996 , vol. 37, # 18 p. 3209 - 3212

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被引用次数: 112

摘要

The REM resin for solid phase synthesis is described. Its use is illustrated by preparing a small array of tertiary amines using a Hofmann elimination reaction. No functional group is required for linking these compounds onto the resin other than the amine constructed during the synthesis.