The synthesis of some alcohols derived from 1, 2, 3, 4-tetrahydroisoquinoline and from 1, 2, 3, 4-tetrahydroquinoline

…, A Šilhánková, S Kafka, P Taufmann…

文献索引：Ferles, Miloslav; Silhankova, Alexandra; Kafka, Stanislav; Taufmann, Petr; Motacek, Tomas Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # l p. 1759 - 1764

全文：HTML全文

被引用次数: 2

摘要

Abstract Reduction of ethyl esters of ω-(1, 2, 3, 4-tetrahydro-2-isoquinolyl) alkanoic acids IVa- e by means of LiAlH 4 was used for the preparation of corresponding primary alcohols Ia-e. 6-(1, 2, 3, 4-Tetrahydro-2-isoquinolyl)-1-hexanol (Ie) was also obtained on reduction of ester amide VII. Reduction of 2-(2-hydroxypropanoyl)-1, 2, 3, 4-tetrahydroisoquinoline (V) with LiAlH 4 gave secondary alcohol II; in the quinoline series alcohol IIIa was obtained in a ...