… Informational Oligomers:(3′→ 2′)??D??Phosphoglyceric Acid Linked Acyclic Oligonucleotides Tagged with 2, 4??Disubstituted 5??Aminopyrimidines as Recognition …

M Hernández??Rodríguez, J Xie…

文献索引：Hernandez-Rodriguez, Marcos; Xie, Jian; Osornio, Yazmin M.; Krishnamurthy, Ramanarayanan Chemistry - An Asian Journal, 2011 , vol. 6, # 5 p. 1252 - 1262

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被引用次数: 1

摘要

Abstract The (3′→ 2′)-phosphodiester glyceric acid backbone containing an acyclic oligomer tagged with 2, 4-disubstituted pyrimidines as alternative recognition elements have been synthesized. Strong cross-pairing of a 2, 4-dioxo-5-aminopyrimidine hexamer, rivaling locked nucleic acid (LNA) and peptide nucleic acid (PNA), with complementary adenine- containing DNA and RNA sequences was observed. The corresponding 2, 4-diamino-and ...