Tetrahedron Letters

Microwave-assisted aza-Prins reaction. Part 1: facile preparation of natural-like 3-azabicyclo [3.3. 1] non-6-enes

V Parchinsky, A Shumsky, M Krasavin

文献索引：Parchinsky, Vladislav; Shumsky, Alexei; Krasavin, Mikhail Tetrahedron Letters, 2011 , vol. 52, # 52 p. 7157 - 7160

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被引用次数: 8

摘要

A facile and operationally simple route to diastereomerically pure, natural-like 3-azabicyclo [3.3. 1] non-6-enes via microwave-assisted, BF3· OEt2-promoted aza-Prins reaction has been developed. Complexity-generating transformations based on these products involving reactive functionalities introduced during the aza-Prins step have been developed.