5-Alkyl-2-(alkylthio)-6-(2, 6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4 (3 H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

A Mai, M Artico, G Sbardella, S Massa…

文献索引：Journal of Medicinal Chemistry, , vol. 42, # 4 p. 619 - 627

全文：HTML全文

被引用次数: 133

摘要

... Journal of Medicinal Chemistry. ... Such chemical modifications impacted the inhibitory activity, especially when two halogen units were introduced at positions 2 and 6 in the phenyl portion of the benzyl group bound to C-6 of the pyrimidine ring. ...