5-Alkyl-2-(alkylthio)-6-(2, 6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4 (3 H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

A Mai, M Artico, G Sbardella, S Massa…

Index: Journal of Medicinal Chemistry, , vol. 42, # 4 p. 619 - 627

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Citation Number: 133

Abstract

... Journal of Medicinal Chemistry. ... Such chemical modifications impacted the inhibitory activity, especially when two halogen units were introduced at positions 2 and 6 in the phenyl portion of the benzyl group bound to C-6 of the pyrimidine ring. ...

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