Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors

G Liu, JK Lynch, J Freeman, B Liu, Z Xin…

文献索引：Journal of Medicinal Chemistry, , vol. 50, # 13 p. 3086 - 3100

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被引用次数: 80

摘要

... Journal of Medicinal ... Metabolic Disease Research, Drug Metabolism, Advanced Technology, Exploratory Pharmacokinetics, Global Pharmaceutical Research and Development ... Our subsequent medicinal chemistry strategy focused on the creation of novel SCD1 inhibitors based ...