Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors

G Liu, JK Lynch, J Freeman, B Liu, Z Xin…

Index: Journal of Medicinal Chemistry, , vol. 50, # 13 p. 3086 - 3100

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Citation Number: 80

Abstract

... Journal of Medicinal ... Metabolic Disease Research, Drug Metabolism, Advanced Technology, Exploratory Pharmacokinetics, Global Pharmaceutical Research and Development ... Our subsequent medicinal chemistry strategy focused on the creation of novel SCD1 inhibitors based ...