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Anticancer anilinoacridines. A process synthesis of the disubstituted amsacrine analog CI??921

ST Brennan, NL Colbry, RL Leeds…

文献索引:Journal of Heterocyclic Chemistry, , vol. 26, # 5 p. 1469 - 1476

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被引用次数: 13

摘要

... 1469 /. Heterocyclic Chem., 26, 1469 (1989). ... Solutions of the isethionic acid salt were found to be stable in sterile water and 5% dextrose over a one day period. The overall yield of CI-921 isethionate utilizing the chemistry shown in Scheme 1 was 62%. ... С Baguley, J. Med. ...