Palladium??Catalyzed C–N Bond Activation: The Synthesis of β??Amino Acid Derivatives from Triethylamine and Acrylates

B Zou, HF Jiang, ZY Wang

文献索引：Zou, Bo; Jiang, Huan-Feng; Wang, Zhao-Yang European Journal of Organic Chemistry, 2007 , # 27 p. 4600 - 4604

全文：HTML全文

被引用次数: 9

摘要

Abstract In the palladium-catalyzed reaction of acrylates, C–N bond activation and acetalization occurred under different conditions. Described herein is a highly efficient palladium-catalyzed C–N bond activation reaction and subsequent new C–N bond formation to directly construct β-amino acids from triethylamine and acrylate esters in isolated yields of up to 95%.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, ...