Tricyclodecenetetracarboxydiimides and their antitumor activity

…, GI Boiko, KA Abdulin, MB Umerzakova…

文献索引：Zhubanov, B. A.; Boiko, G. I.; Abdulin, K. A.; Umerzakova, M. B.; Ibraeva, Zh. K. Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 1 p. 38 - 40 Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 1 p. 43 - 44

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摘要

The unsubstituted tricyclodecenetetracarboxydiimide (I) was obtained by reacting tricyclodecenetetracarboxylic dianhydride (the adduct of benzene and maleic anhydride, AB) with aqueous ammonia, followed by thermal imidation under reduced pressure, or by reaction with gaseous ammonia in solution in N, N'dimethylformamide (DMF)[2]. Reaction of AB with leucine and e-leucine gave the N, N'-disubstituted compounds (II) and (III).