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Substrate specificity of glycyrrhizinic acid hydrolase.

Y Sasaki, T Morita, T Kuramoto, K MIZUTANI…

文献索引:Sasaki, Yasuhiro; Morita, Toshinobu; Kuramoto, Takashi; Mizutani, Kenji; Ikeda, Ryuko; Tanaka, Osamu Agricultural and Biological Chemistry, 1988 , vol. 52, # 1 p. 207 - 210

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被引用次数: 22

摘要

Glycyrrhizinic acid hydrolase produced by Aspergillus niger selectively hydrolyzed the 3-O-β- D-glucuronide linkage of glycyrrhizinic acid. The substrate specificity of this enzyme was investigated for synthetic glucuronides of aliphatic alcohols as well as natural glucuronide saponins. It was revealed that the glucuronide linkage with low molecular weight alcohols was not cleaved by this enzyme, while the 3-O-β-D-glucuronide linkage of saponins of ...