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Tetrahedron letters

Synthesis of seven-membered oxacycles. Part 2: The furan approach

Y Fall, B Vidal, D Alonso, G Gómez

文献索引:Fall, Yagamare; Vidal, Beatriz; Alonso, David; Gomez, Generosa Tetrahedron Letters, 2003 , vol. 44, # 24 p. 4467 - 4469

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被引用次数: 41

摘要

Seven-membered oxacycles are structural units that are present in a wide variety of bioactive natural products, 1., , , , , , and including the monocyclic zoapatanol, 2., , and the polycyclic hemibrevetoxin B 3., , and (Fig. 1) and more complex polyether toxins such as ciguatoxin 4., and and brevetoxins A and B. 5 Because of their unusual molecular architecture, these molecules are challenging synthetic targets for organic chemists. ... We recently described the synthesis of seven- ...