A general approach to 5-substitution of 3-furaldehydes

…, JM Holmes, DA Harcourt, ME Garst

文献索引：Lee, Gary C. M.; Holmes, Judy M.; Harcourt, Dale A.; Garst, Michael E. Journal of Organic Chemistry, 1992 , vol. 57, # 11 p. 3126 - 3131

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被引用次数: 26

摘要

Herein we report the details of the conversion of 3-furaldehyde into 2-substituted 4- furaldehydes and the transformations of 2-substituted 4-furaldehydes and Csubstituted 3- furaldehydes into tri-and tetraeubstituted furans. We have developed a new disubstituted furan Synthesis by applying metalation to the direct conversion of% substituted furans into 2, Cdiaubstituted furans. In situ protection of% furaldehyde with lithium morpholide followed ...