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Process Research for Multikilogram Production of Etamicastat: A Novel Dopamine β-Hydroxylase Inhibitor

A Beliaev, J Wahnon, D Russo

文献索引:Organic Process Research and Development, , vol. 16, # 4 p. 704 - 709

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被引用次数: 10

摘要

... Pd complex, base, heating in organic solvent; d) CuI, DMEDA, base, heating in organic solvent. ... latter to the target ene-carbamate 22 was achieved according to the published procedure,(24) with ... of the acid 30 to 1 was achieved via a two-step Curtius process involving isolation ...