Tetrahedron Letters

Convenient method for the synthesis of phthalazinones via carbonylation of 2-bromobenzaldehyde using Co 2 (CO) 8 as a CO source

AS Suresh, P Baburajan, M Ahmed

文献索引：Suresh, A. Sivalingam; Baburajan, Poongavanam; Ahmed, Mansur Tetrahedron Letters, 2014 , vol. 55, # 24 p. 3482 - 3485

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被引用次数: 7

摘要

Abstract A simple one-pot synthesis of phthalazinones by the condensation and intra- molecular carbonylative cyclization of 2-bromobenzaldehydes with hydrazines is reported. This method utilizes solid Co 2 (CO) 8 as carbonyl source making it readily accessible in small-scale laboratory applications.