Extending the utility of [Pd (NHC)(cinnamyl) Cl] precatalysts: Direct arylation of heterocycles
AR Martin, A Chartoire, AMZ Slawin…
文献索引：Martin, Anthony R.; Chartoire, Anthony; Slawin, Alexandra M.Z.; Nolan, Steven P. Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1637 - 1643
Abstract The use of [Pd (NHC)(cinnamyl) Cl] precatalysts in the direct arylation of heterocycles has been investigated. Among four different precatalysts,[Pd (SIPr)(cinnamyl) Cl] proved to be the most efficient promoter of the reaction. The C–H functionalization of sulfur-or nitrogen-containing heterocycles has been achieved at low catalyst loadings. These catalyst charges range from 0.1 to 0.01 mol% palladium.
