Bispidine as a secondary structure nucleator in peptides

…, S Sadanandan, YK Sharma, S Chinthalapalli…

文献索引：Haridas; Sadanandan, Sandhya; Sharma, Yogesh K.; Chinthalapalli, Srinivas; Shandilya, Ashutosh Tetrahedron Letters, 2012 , vol. 53, # 6 p. 623 - 626

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被引用次数: 13

摘要

Here we describe bispidine as a scaffold for inducing open turn-like and beta sheet conformations on the attached peptides depending on the mode of attachment of peptides to the scaffold. Various bispidine–peptide conjugates were designed and synthesized to demonstrate the versatility of the scaffold.