Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform

B Desai, K Dixon, E Farrant, Q Feng…

文献索引：Journal of Medicinal Chemistry, , vol. 56, # 7 p. 3033 - 3047

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被引用次数: 29

摘要

... Journal of Medicinal Chemistry. ... Some chemistry development time is required to ensure that analogues can be made in a microfluidic reactor, and the efficient resolution of synthetic chemistry challenges is critical to the success of this approach. ...