Tetrahedron

A Novel synthesis of 2-imino-4-thiazolines via α-bromoketimines

N De Kimpe, M Boelens, JP Declercq

文献索引：De Kimpe, Norbert; Boelens, Mark; Declercq, Jean-Paul Tetrahedron, 1993 , vol. 49, # 16 p. 3411 - 3424

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被引用次数: 27

摘要

A novel straightforward synthesis of 2-imino-4-thiazolines has been performed by reaction of α-bromoketimines with potassium thiocyanate in acetonitrile. Contrary to other syntheses of these heterocycles, no side reactions were observed. The structural assignment of these relatively rare 2-imino-2, 3-dihydrothiazoles was executed by spectroscopic means, by the synthesis of model compounds by an alternative route and by X-ray crystallographic ...