Tetrahedron letters

New approach to the synthesis of deoxynucleoside-phosphoramidite derivatives

T Tanaka, S Tamatsukuri, M Ikehara

文献索引：Tanaka, Toshiki; Tamatsukuri, Sigeru; Ikehara, Morio Tetrahedron Letters, 1986 , vol. 27, # 2 p. 199 - 202

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被引用次数: 49

摘要

Abstract A new method for the synthesis of deoxyribonucleoside-phosphoramidite via an intermediate, 5′-0-dimethoxytritylthymidine-3′-0-diisopropylamino-phosphorochloridite, is reported. By using this method, several deoxyribonucleoside phosphoramidite derivatives with different protecting groups at phosphorus including P S and P N bond besides P O bond were synthesized.