Nitrile-promoted Rh-catalyzed intermolecular hydroacylation of olefins with salicylaldehyde

…, S Nagumo, N Kawahara, H Suemune

文献索引：Imai, Masanori; Tanaka, Masakazu; Nagumo, Shinji; Kawahara, Norio; Suemune, Hiroshi Journal of Organic Chemistry, 2007 , vol. 72, # 7 p. 2543 - 2546

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被引用次数: 36

摘要

Rh-catalyzed intermolecular hydroacylation between salicylaldehyde and alkenylnitriles proceeded at room temperature to preferentially give normal-hydroacylated products. Addition of CH3CN and NaOAc accelerated the Rh-catalyzed hydroacylation of monoolefins to exclusively produce the normal-hydroacylated products under mild reaction conditions. Plausible mechanisms for the regioselections are also described.