… fluorination of hexahydroazepine, methylpiperidines and methyl 1-hexahydroazepine-acetate: the preparation of F-(1-hexahydroazepine-acetyl fluoride) and its …
The electrochemical fluorination of hexahydroazepine (1), methylpiperidines (2)[2- methylpiperidine (2a), 3-methylpiperidine (2b), 4-methylpiperidine (2c)] and methyl 1- hexahydroazepine-acetate (3) was examined. An extensive cleavage of the C–N bond occurred in the fluorination of secondary cyclic amines (1, 2a–c) resulting in only a small yield of the corresponding F-(N-fluoro cyclic amines). F-(1-hexahydroazepine-acetyl ...
