Synthesis

A Practical Method for the Reformatsky Reaction of Aldehydes

A Chattopadhyay, A Salaskar

文献索引：Chattopadhyay, Angshuman; Salaskar, Avinash Synthesis, 2000 , # 4 p. 561 - 564

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被引用次数: 28

摘要

Abstract: Reformaksky reaction of aliphatic aldehydes has been performed successfully by the addition of BF3• OEt2 to a stirred suspension of aldehyde, bromo ester and Zn dust in aqueous THF. For aromatic aldehydes, addition of benzoyl peroxide is also required to effect the reaction. Key words: aqueous condition, boron trifluoride etherate, stereoselectivity, chemoselectivity, radical chain mechanism.