Tetrahedron

Chemoselective Heck arylation of acrolein diethyl acetal catalyzed by an oxime-derived palladacycle

C Nájera, L Botella

文献索引：Najera, Carmen; Botella, Luis Tetrahedron, 2005 , vol. 61, # 41 p. 9688 - 9695

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被引用次数: 23

摘要

A dimeric 4-hydroxyacetophenone oxime-derived palladacycle has been used as a very efficient precatalyst for the chemoselective arylation of acrolein diethyl acetal to give either cinnamaldehyde derivatives or 3-arylpropanoate esters by proper choice of the reaction conditions. The synthesis of cinnamaldehyde derivatives can be performed by Heck reaction of acrolein diethyl acetal with iodo-, bromo-or chloroarenes in N, N-dimethylacetamide ( ...