Tetrahedron

Synthesis of α-galactosyl ceramide analogues with an α-triazole at the anomeric carbon

AW McDonagh, PV Murphy

文献索引：McDonagh, Anthony W.; Murphy, Paul V. Tetrahedron, 2014 , vol. 70, # 19 p. 3191 - 3196

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被引用次数: 6

摘要

Abstract The synthesis of 1, 2, 3-triazole containing analogues of α-GalCer and galacturonic acid containing Sphingomonous cell wall antigens is described. Anomerisation was used to provide the required α-glycosyl azide precursor. Copper azide–alkyne cycloaddition (CuAAC) generated the α-triazole linkage.