Tetrahedron letters

Reduction of α-substituted succinonitriles with diisobutylaluminum hydride: a facile method for the synthesis of 3-substituted pyrroles

JH Babler, KP Spina

文献索引：Babler, James H.; Spina, Kenneth P. Tetrahedron Letters, 1984 , vol. 25, # 16 p. 1659 - 1660

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被引用次数: 22

摘要

Abstract Treatment of four representative α-substituted succinonitriles (2) with diisobutylaluminum hydride, followed by hydrolysis of each reaction mixture with aqueous sodium dihydrogen phosphate, afforded 3-substituted pyrroles (4) in approximately 50% yield.