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Tetrahedron letters

Simple deprotection of acetal type protecting groups under neutral conditions

H Miyake, T Tsumura, M Sasaki

文献索引:Miyake, Hideyoshi; Tsumura, Takatsugu; Sasaki, Mitsuru Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7213 - 7215

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被引用次数: 18

摘要

When acetals such as MOM ethers, MEM ethers, and THP ethers were heated in ethylene glycol or propylene glycol, solvolysis proceeded smoothly to produce alcohols in excellent yield. This reaction is a very promising method for chemoselective deprotection of acetal type protecting groups.