Pharmacology

Inhibition of urea transport across renal tubules by pyrazinoylguanidine and analogs

KH Beyer Jr, RT Gelarden, ES Vesell

文献索引：Cragoe et al. Journal of Organic Chemistry, 1958 , vol. 23, p. 971,978

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被引用次数: 12

摘要

... This led us to the chemical structure activity selection and development of PZG as an inhibitor of urea reabsorption by the kidney ... Transverse sections of the cortex, outer and inner medulla were weighed and homoge- nized in a known volume of distilled water, and ... 2). Baer et al. ...