Pharmacology

Inhibition of urea transport across renal tubules by pyrazinoylguanidine and analogs

KH Beyer Jr, RT Gelarden, ES Vesell

Index: Cragoe et al. Journal of Organic Chemistry, 1958 , vol. 23, p. 971,978

Full Text: HTML

Citation Number: 12

Abstract

... This led us to the chemical structure activity selection and development of PZG as an inhibitor of urea reabsorption by the kidney ... Transverse sections of the cortex, outer and inner medulla were weighed and homoge- nized in a known volume of distilled water, and ... 2). Baer et al. ...