Tetrahedron

Synthesis of chiral 2-(anilinophenylmethyl) pyrrolidines and 2-(anilinodiphenylmethyl) pyrrolidine and their application to enantioselective borane reduction of …

…, H Kamito, M Takano, Y Takebe, Y Yamaguchi…

文献索引：Hosoda, Naoya; Kamito, Hideaki; Takano, Miki; Takebe, Yoshitaka; Yamaguchi, Yoshitaka; Asami, Masatoshi Tetrahedron, 2013 , vol. 69, # 6 p. 1739 - 1746

全文：HTML全文

被引用次数: 8

摘要

Chiral diamines, 2-(anilinophenylmethyl) pyrrolidines and 2-(anilinodiphenylmethyl) pyrrolidine, were prepared from N-(tert-butoxycarbonyl) pyrrolidine or (S)-proline as a starting material, respectively. These chiral diamines were efficient for the catalytic enantioselective borane reduction of acetophenone. Using (S)-2-(anilinodiphenylmethyl) pyrrolidine, chiral secondary alcohols were obtained from prochiral ketones with good to ...