Tetrahedron Letters

Investigations into the parallel kinetic resolution of acetyl mandelic acid

S Chavda, E Coulbeck, J Eames

文献索引：Chavda, Sameer; Coulbeck, Elliot; Eames, Jason Tetrahedron Letters, 2008 , vol. 49, # 52 p. 7398 - 7402

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被引用次数: 2

摘要

The resolution of a series of active esters (derived from acetyl mandelic acid) using an equimolar combination of quasi-enantiomeric oxazolidin-2-ones is discussed. The levels of diastereoselectivity and the facial selectivity were found to be dependent on the structural nature of the pro-leaving group.