Ruthenium-catalyzed reductive cyclization of nitroarenes with trialkylamines leading to quinolines

CS Cho, TK Kim, BT Kim, TJ Kim, SC Shim

文献索引：Cho, Chan Sik; Kim, Tae Kyung; Kim, Bok Tae; Kim, Tae-Jeong; Shim, Sang Chul Journal of Organometallic Chemistry, 2002 , vol. 650, # 1-2 p. 65 - 68

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被引用次数: 48

摘要

Nitroarenes react with trialkylamines in the presence of a catalytic amount of a ruthenium catalyst together with tin (II) chloride dihydrate at 180° C in an aqueous medium (toluene– H2O) to afford the corresponding quinolines in moderate to good yields. The catalytic pathway seems to be proceeded via a sequence involving initial reduction of nitroarenes to anilines, alkyl group transfer from alkylamines to anilines to form an imine, dimerization of ...