Australian Journal of Chemistry

The synthesis and mass spectra of some Dihydrofuro [2, 3-b] pyridines

JW Ducker, BK Williams

文献索引：Ducker,J.W.; Williams,B.K. Australian Journal of Chemistry, 1978 , vol. 31, p. 2327 - 2331

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被引用次数: 3

摘要

Continuing our studies on organic polycyano compounds1 we have investigated the reaction of the sodium salt of malononitrile dimer2 with various oxirans and/3-chloro alcohols. The reaction proceeds readily, giving good yields of the dihydrofuropyridines (1). The reaction may be interpreted as an initial opening of the oxiran ring (or nucleophilic replacement of chlorine) followed by successive nucleophilic additions to the nitrile ...