A convenient synthesis of novel pyrido (1′, 2′: 1, 2) imidazo [5, 4??d]??1, 2, 3??triazinones from imidazo [1, 2??a] pyridines

…, E Campos, R Jimenez, A Reyes

文献索引：Zamora, Hector Salgado; Rizo, Benito; Campos, Elena; Jimenez, Rogelio; Reyes, Alicia Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 1 p. 91 - 94

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被引用次数: 7

摘要

Abstract The imidazo [1, 2-a] pyridine system was investigated as a synthon for the building of very attractive fused triazines, a planar, angular tri-heterocycle with potential biological activity. Thus ethyl 3-nitroimidazo [1, 2-a] pyridine-2-carboxylate was treated with ammonia or with an excess of primary amines to generate the corresponding substituted nitro carboxamidoimidazopyridines. The nitro substituent in the latter products, was reduced to ...