Tetrahedron

Solvent-free and direct C (sp 3)–H amination of adamantanes by grinding

Z Wei, J Li, N Wang, Q Zhang, D Shi, K Sun

文献索引：Wei, Zhen; Li, Jiarong; Wang, Ning; Zhang, Qi; Shi, Daxin; Sun, Kening Tetrahedron, 2014 , vol. 70, # 7 p. 1395 - 1400

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被引用次数: 9

摘要

Abstract A facile, direct and environmentally benign conversion of C (sp 3)–H bonds to C (sp 3)–N bonds using substoichiometric amount of aprotic superelectrophiles polyhalomethane– AlX 3 has been achieved by grinding under solvent-free conditions at room temperature in air. It is a general and simple method for the direct amination of adamantanes, and a series of aminoadamantanes of azoles, arylamines or heteroarylamines were obtained in good ...