Molecules

Efficient TCT-catalyzed synthesis of 1, 5-benzodiazepine derivatives under mild conditions

CW Kuo, CC Wang, V Kavala, CF Yao

文献索引：Kuo, Chun-Wei; Wang, Chun-Chao; Kavala, Veerababurao; Yao, Ching-Fa Molecules, 2008 , vol. 13, # 9 p. 2313 - 2325

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被引用次数: 23

摘要

Abstract: 2, 4, 6-Trichloro-1, 3, 5-triazine (TCT) efficiently catalyzed the condensation reactions between 1, 2-diamines and various enolizable ketones to afford 1, 5- benzodiazepines in good to excellent yields. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are notable features of this method.