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Synthesis and evaluation of analgesic, antiinflammatory and antiplatelet properties of new 2-pyridylarylhydrazone derivatives

AR Todeschini, ALP de Miranda, KCM da Silva…

文献索引:Todeschini, Adriane R.; De Miranda, Ana Luisa P.; Da Silva, Kelly Christine M.; Parrini, Sergio C.; Barreiro, Eliezer J. European Journal of Medicinal Chemistry, 1998 , vol. 33, # 3 p. 189 - 199

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被引用次数: 184

摘要

This work describes recent results from our research program aiming at the synthesis and pharmacological evaluation of new compounds acting as antiinflammatory, analgesic and platelet antiaggregatory. In this paper the synthesis and the pharmacological profile as analgesic, antiinflammatory and anti-platelet of new functionalized 2-pyridylarylhydrazone derivatives 5a–r are discussed. This class of N-heterocyclic derivatives represents a new ...